Hypertrophic Cardiomyopathy HCM

Hypertrophic Cardiomyopathy is the most commonly diagnosed disease in cats.
HCM is characterized by abnormal thickening of the left ventricle (pumping chamber). When the left ventricle becomes severely thickened, it cannot fill properly. This results in increased pressure in the left ventricle, and enlargement of the left atrium (collecting chamber). Many cats with HCM do not experience clinical problems. In some cats, HCM progresses slowly. Other cats may develop problems spontaneously, after steroids or IV fluid administration or following general anesthesia.
Potential complications of HCM
Congestive Heart Failure (CHF): Signs of CHF include increased respiratory rate or effort, lethargy, and decreased appetite. CHF can be managed with medications.
Aortic Thromboembolism (ATE): This occurs when a blood clot forms in an enlarged left atrium and embolizes (dislodges), most commonly to the hind limbs. The most common sign of ATE is the sudden inability to use the hind limbs.

Monitor & Treatments

Monitor

Physical Examination: Cats with HCM frequently (but not always) have a heart murmur. An arrhythmia (irregular heart rhythm) or gallop (extra heart sound) is sometimes detected. It is not possible to determine the severity of heart disease based on examination alone.

Echocardiography (Heart Ultrasound): Echocardiography is the best test for HCM. It allows us to evaluate the thickness and function of the heart muscle, to assess the size of the left atrium, and to detect clot formation.

Thoracic Radiographs (Chest X-rays): Chest X-rays are often taken to look for evidence of congestive heart failure. Many cats with mild to moderate HCM will have relatively normal-looking hearts on X-ray.

Bloodwork & Urine Testing: Full bloodwork and urine testing is recommended to assess for underlying diseases that can cause thickening of the heart muscle. These include hyperthyroidism and systemic hypertension related to kidney disease. BNP is a blood test that may be used to screen for heart disease and monitor progression of disease in some patients.

Treatment

Clopidolgrel (Plavix): Low molecular weight heparin can also be used to prevent clot formation. Enoxaparin is only available in injectable form. Some cats with HCM also have Systolic Anterior Motion (SAM) of the mitral valve. These cats may be prescribed a beta-blocker such as Atenolol.

Enoxaparin (Lovenox):In its early stages, HCM may only require monitoring. Based on the echocardiographic assessment, these medications may be prescribed.

Atenolol (Or Other Beta Blocker):Plavix may be prescribed when the left atrium becomes enlarged due to increased risk of clot formation. Studies have shown that Plavix is more effective than aspirin at preventing clotting.

Commonly Used Medications

  • Furosemide (Lasix): Furosemide is a diuretic used to treat heart failure, by removing fluid from the lungs. It commonly causes increased drinking and urination.
  • Pimobendan (Vetmedin): Pimobendan is an inodilator: a combination of positive inotrope (improves contraction of the heart) and vasodilator (dilates blood vessels). This results in more ecient contraction of the heart.
  • ACE Inhibitor (Benazepril or Enalapril): An ACE (Angiotensin Converting Enzyme) inhibitor is a type of medication that prevents the production of Angiotensin II which promotes increased blood pressure and fluid retention.

Frequently Asked Questions

What causes HCM in cats?

In many cats, HCM is believed to be genetic. Certain breeds, such as Maine Coons and Ragdolls, have a known inherited risk. In other cases, the cause is unknown.

What are the signs I should watch for?

  • Rapid or labored breathing
  • Lethargy or decreased activity
  • Decreased appetite
  • Weakness or collapse
  • Sudden hind limb paralysis (from a blood clot in severe cases)
  •  

Can HCM be detected before symptoms appear?

Yes. Cats may be diagnosed during routine screening exams or because of a heart murmur or abnormal imaging before they show clinical signs.

What is the prognosis for cats with HCM?

Prognosis varies widely. Some cats live for years with mild disease, while others may develop complications more quickly. Early detection and management improve outcomes.

How can I schedule an appointment? 

Please call us at 720-510-7707 to book a consultation today.